Diastereo- and enantio-selective synthesis of 6-heterosubstituted-3,5-dihydroxyesters: Novel precursors of mevinolin analogues

DOI: 10.1039/cc9960000609

Source and publish data:

Chemical Communications p. 609 - 610 (1996)

Update date:2022-08-03

Topics:

Authors:

Enders, Dieter

Burkamp, Frank

Runsink, Jan

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/cc9960000609

The diastereoselective addition of 1,3 -bis(trimethylsilyloxy)-1-methoxybutadiene 2 to readily available α-heterosubstituted aldehydes (S)-1 affords after syn-diastereoselective reduction HMG-CoA-reductase inhibitor-precursors (S,R,S)-4 and 5 with various

Full text of DOI:10.1039/cc9960000609

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:Octanoic acid, 6-[bis(phenylmethyl)amino]-5-hydroxy-7,7-dimethyl-3-oxo-, methyl ester, (5R,6S)-

Cas No:176381-65-0

R&D Labs maybe for 176381-65-0

Zhushan County Tianxin Pharmaceutical & Chemical Co., Ltd.

Contact:0086-719-4224892

Address:Tutang Road, Chengguan Town, Zhushan County, Hubei Province
Huangshan Violet Biological Technology Co., Ltd

Contact:+86-559-2335676

Address:16-201 JinShanYuan,JiangNan New City,TunXi District,HuangShan City,AnHui Province,China
Ji'an Hairui Natural Plant Co. Ltd.

Contact:0796-8105528

Address:Meilin industry park, Qingyuan district Ji'an City, Jiangxi Province
Jiangsu Taihu New Materials Holding Co., Ltd

Contact:+86-519-86160108

Address:Xueyan Town, Changzhou City, Jiangsu Province, 213169, China
Quzhou Ruiyuan chemical Co., Ltd

Contact:+86-570-3039321/3039361/3039308

Address:18# Huayang Road,Quzhou High-tech Industrial Park, Zhejiang China.

Relevant to this article

Synthesis and NMR study of two lipophilic iron(III) sequestering agents based on 8-hydroxyquinoline; H-bonding and conformationsl changes

Doi:10.1016/0040-4020(96)00166-4
(1996)
Branched peptides and conformationally constrained analogues from cyanomethyleneamino pseudopeptides

Doi:10.1016/0040-4039(96)00198-0
(1996)
Doi:10.1021/ja01200a043
(1947)
Synthesis of highly functionalized γ-lactam derivatives for use as conformational constraints in peptides

Doi:10.1016/0040-4039(96)00296-1
(1996)
Intramolecular Diels-Alder additions to 2-benzopyran-3-ones; endo-selective additions and some reactions of the adducts

Doi:10.1039/P19960000705
(1996)
Thermodynamic control of quantum defects on single-walled carbon nanotubes

Doi:10.1039/c9cc05623h
(2019)

Article Doi