Tetrahedron Letters p. 2471 - 2474 (1996)
Update date:2022-08-03
Topics:
Martin-Martinez, Mercedes
Garcia-Lopez, Ma Teresa
Herranz, Rosario
Gonzalez-Muniz, Rosario
A series of highly functionalized 2-oxopyrrolidine derivatives, as tripeptidemimetics in which the amino acid side chains are mounted on the γ-lactam template, were synthesized by nucleophilic opening of the δ-lactam system of the corresponding 3,6-dioxopyrrolo[1,2-a]pyrazine bicyclic analogues.
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