Deuterated antimalarials: Synthesis of trideutero- artemisinin, dihydroartemisinin, and arteether

DOI: 10.1002/(SICI)1099-1344(199603)38:3<249::AID-JLCR840>3.0.CO;2-D

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 249 - 254 (1996)

Update date:2022-07-29

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Authors:

Avery, Mitchell A.

Bonk, Jason D.

Mehrotra, Sanjiv

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Article abstract of DOI:10.1002/(SICI)1099-1344(199603)38:3<249::AID-JLCR840>3.0.CO;2-D

The stereoselective total synthesis of the antimalarial agents artemisinin-d₃ (1), dihydroartemisinin-d₃ (2), and arteether-d₃ (3), incorporating ²H at C-16 (C-9 methyl) is reported.

Full text of DOI:10.1002/(SICI)1099-1344(199603)38:3<249::AID-JLCR840>3.0.CO;2-D

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