1',5'-Anhydrohexitol oligonucleotides: Synthesis, base pairing and recognition by regular oligodeoxyribonucleotides and oligoribonucleotides

DOI: 10.1002/chem.19970030118

Source and publish data:

Chemistry - A European Journal p. 110 - 120 (1997)

Update date:2022-07-31

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Authors:

Hendrix, Chris

Rosemeyer, Helmut

Verheggen, Ilse

Seela, Frank

Van Aerschot, Arthur

Herdewijn, Piet

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Article abstract of DOI:10.1002/chem.19970030118

Oligonucleotides constructed of 1',5'-anhydrohexitol nucleoside building blocks (hexitol nucleic acids, HNA) are completely stable towards 3'-exonuclease and form very stable self-complementary duplexes as well as sequence-selective stable duplexes with t

Full text of DOI:10.1002/chem.19970030118

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