Polycondensed heterocycles. IX. Pyrrolo[2,1-c][1,4]benzothiazepines. Synthesis of 3-(dimethylamino)methyl derivatives

DOI: 10.1016/S0040-4020(96)00342-0

Source and publish data:

Tetrahedron p. 7745 - 7754 (1996)

Update date:2022-07-31

Topics:

Authors:

Garofalo, Antonio

Campiani, Giuseppe

Ciani, Silvia M.

Fiorini, Isabella

Nacci, Vito

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Article abstract of DOI:10.1016/S0040-4020(96)00342-0

The synthesis of 3-(dimethylamino)methyl-5H,11H-pyrrolo[2,1- c][1,4]benzothiazepine derivatives 2a-c which might show significant central nervous system (CNS) activity, is described. The basic side chain was introduced by a Mannich condensation with the p

Full text of DOI:10.1016/S0040-4020(96)00342-0

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