Chloropalladation of propargyl thioethers: A facile synthesis of cyclopalladated compounds

Article abstract of DOI:10.1016/0277-5387(95)00572-2

The reaction of the propargyl thioethers Ph - C≡C - CH(R₁)SR (R = Me, Prⁱ, Ph and R₁ = H, Me) with Li₂PdCl₄ in methanol at room temperature produced in very good yields (70-90%) five-membered palladocycles [Pd(C(Ph)=C(Cl)CH(R₁)SR)(μCl)]₂. Under the same reaction conditions the homopropargylthioether Ph - C≡C - (CH₂)₂SPh yielded unexpectedly the complex {Pd[S(Ph)(CH₂)₃C=O(Ph)](Cl)(μ-Cl)}₂ resulting from the hydrolysis of the C≡C bond.