Synthesis biological and biological evaluation of some acyclic pyridine C-nucleosides. Part two

Article abstract of DOI:10.1080/07328319608007388

3-Bromo-5-(2-hydroxyethylthiomethyl)pyridine (7) was synthesized by reaction of 3-bromo-5-chloromethylpyridine hydrochloride (6) with the mono sodium salt of 2-mercaptoethanol. 3-Bromo-5-hydroxymethylpyridine (10) was, after protection as a silyl ether, c

Full text of DOI:10.1080/07328319608007388

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Nucleosides and Nucleotides
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Synthesis and Biological Evaluation of
Some Acyclic Pyridine C-Nucleosides.
Part Two
Johan Van hemel a , Eddy L. Esmans a , Alex De Groot b , Roger
A. Dommisse b , Jan M. Balzarini c & Erik D. De Clercq c
a Nucleoside Research Unit , University of Antwerp (RUCA) ,
Groenenborgerlaan 171, B-2020, Antwerp, BELGIUM
b NMR Research Unit , University of Antwerp (RUCA) ,
Groenenborgerlaan 171, B-2020, Antwerp, BELGIUM
c Rega Institute for Medical Research , Katholieke Universiteit
Leuven , Minderbroedersstraat 10, B-3000, Leuven, BELGIUM
Published online: 19 Aug 2006.
To cite this article: Johan Van hemel , Eddy L. Esmans , Alex De Groot , Roger A. Dommisse ,
Jan M. Balzarini & Erik D. De Clercq (1996) Synthesis and Biological Evaluation of Some
Acyclic Pyridine C-Nucleosides. Part Two, Nucleosides and Nucleotides, 15:6, 1203-1221, DOI:
10.1080/07328319608007388
To link to this article: http://dx.doi.org/10.1080/07328319608007388
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