Synthesis of 3-methyl-substituted pyrazolotriazolopyrimidin-4-one and pyrazolothiazolopyrimidin-4-one derivatives

Article abstract of DOI:10.1002/jhet.5570330239

As a part of a research on anti-inflammatory analgesic compounds 3-methyl substituted pyrazolotriazolopyrimidin-4-one and pyrazolothiazolopyrimidin-4-one derivatives were prepared by previously reported procedures. None of the compounds showed improved activity when compared with the previously reported unsubstituted analogs.