New approach to solid phase synthesis of polyamide nucleic acids analogues (PNA) and PNA-DNA conjugates

DOI: 10.1016/0040-4039(96)00624-7

Source and publish data:

Tetrahedron Letters p. 3571 - 3574 (1996)

Update date:2022-08-03

Topics:

Authors:

Stetsenko, Dmitry A.

Lubyako, Elena N.

Potapov, Viktor K.

Azhikina, Tatyana L.

Sverdlov, Evgeny D.

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Article abstract of DOI:10.1016/0040-4039(96)00624-7

New version of sequential DNA and polyamide solid phase synthesis is applied to the preparation of PNA and PNA-DNA conjugates bearing free 3'-end. N-Mmt protected uracil and thymine PNA monomers are obtained in high yields. Novel support derived from TSK

Full text of DOI:10.1016/0040-4039(96)00624-7

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