Palladium catlyzed reductive cyclization reaction in alkaloid synthesis - an enantioselective total synthetic route to (+)-pumiliotoxin C

Article abstract of DOI:10.1016/0040-4039(96)00861-1

Beginning with the chirally homogeneous cyclohexenol 3, an enantioselective total synthetic route to (+)-pumiliotoxin C (1) has been described. Palladium catalyzed reductive cyclization reaction was employed to prepare a key component in the synthesis. Co