Antitumor Agents. 155. Synthesis and Biological Evaluation of 3',6,7-Substituted 2-Phenyl-4-quinolones as Antimicrotubule Agents

DOI: 10.1021/jm00046a025

Source and publish data:

Journal of Medicinal Chemistry p. 3400 - 3407 (1994)

Update date:2022-09-26

Topics:

Authors:

Li, Leping

Wang, Hui-Kang

Kuo, Sheng-Chu

Wu, Tian-Shung

Mauger, Anthony

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00046a025

A series of 3',6,7-substituted 2-phenyl-4-quinolones were designed and synthesized as antimitotic antitumor agents. All compounds showed cytotoxic effects (log GI50 View More

Full text of DOI:10.1021/jm00046a025

Products guided by the article

Product name:N-(6-Acetyl-benzo[1,3]dioxol-5-yl)-3-nitro-benzamide

Cas No:178983-58-9

R&D Labs maybe for 178983-58-9

Jiaozuo Zhongwei Special Products Pharmaceutical Co.,Ltd.

website:http://www.zw-pvp.com

Contact:15302105619

Address:Jiaozuo,Henan,China (Mainland)
Yurui(Shanghai)Chemical Co.,Ltd

Contact:0086 21-50456736

Address:No.3188 Xiupu Road,Shanghai
wuxi leji biology technology co., LTD

website:http://www.lejibio.com/

Contact:18362718864

Address:The Nanyue Road No. 2, Yixing City, Jiangsu Province
SAGECHEM LIMITED

website:http://www.sagechem.com

Contact:+86-571-86818502

Address:Room C1301, New Youth Plaza, 8 Jia Shan Road, Hangzhou, China
Jiaozuo Zhongwen Trading Coporation Limited

Contact:--

Address:East Renmin Road

Relevant to this article

Influence of intramolecular hydrogen-bonding on the conformation of 3-deoxy-3-thioureido sugars

Doi:10.1016/0008-6215(96)00039-0
(1996)
Doi:10.1007/BF00481584
()
Anion cryptates: Synthesis, crystal structures, and complexation constants of fluoride and chloride inclusion complexes of polyammonium macrobicyclic ligands

Doi:10.1002/hlca.19960790302
(1996)
Room temperature cyclopentadiene elimination reaction for the synthesis of diethylgallium-amides, -phosphides, and -thiolates. Crystal and molecular structures of [Et₂GaP(t-Bu)₂]₂ and [Et₂GaS(SiPh₃)]<

Doi:10.1021/om960284p
(1996)
Nucleophilic Substitution Reaction Of 1-Hydroxytryptophan And 1-Hydroxytryptamine Derivatives (Regioselective Syntheses Of 5-Substituted Derivatives Of Tryptophan And Tryptamine)

Doi:10.3987/COM-93-6391
(1993)
Exo,exo-2,3-diaminoborneol-derived imidazolidinone as chiral auxiliary for asymmetric alkylations

Doi:10.1016/0040-4039(96)00847-7
(1996)

Article Doi