Nucleophilic Substitution Reaction Of 1-Hydroxytryptophan And 1-Hydroxytryptamine Derivatives (Regioselective Syntheses Of 5-Substituted Derivatives Of Tryptophan And Tryptamine)

DOI: 10.3987/COM-93-6391

Source and publish data:

Heterocycles p. 1859 - 1866 (1993)

Update date:2022-09-26

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Authors:

Somei, Masanori

Fukui, Yoshikazu

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Article abstract of DOI:10.3987/COM-93-6391

Regioselective nucleophilic substitution at the 5-position of indole nucleus was observed in the reaction of 1-hydroxytryptophan and 1-hydroxytryptamine derivatives with acids, suggesting the mechanism of serotonin formation in the central nervous system.

Full text of DOI:10.3987/COM-93-6391

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