
Chemical and Pharmaceutical Bulletin p. 552 - 555 (2000)
Update date:2022-08-03
Topics:
Takami, Hitoshi
Nonaka, Hiromi
Kishibayashi, Nobuyuki
Ishii, Akio
Kase, Hiroshi
Kumazawa, Toshiaki
A series of 4-phenoxybutyric acid derivatives attached to a tricyclic skeleton were prepared and evaluated as 5α-reductase inhibitors. Structure activity relationships for these compounds in terms of rat epididymis (type 2) 5α-reductase inhibitory activit
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