Synthesis of tricyclic compounds as steroid 5α-reductase inhibitors

DOI: 10.1248/cpb.48.552

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Chemical and Pharmaceutical Bulletin p. 552 - 555 (2000)

Update date:2022-08-03

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Authors:

Takami, Hitoshi

Nonaka, Hiromi

Kishibayashi, Nobuyuki

Ishii, Akio

Kase, Hiroshi

Kumazawa, Toshiaki

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Article abstract of DOI:10.1248/cpb.48.552

A series of 4-phenoxybutyric acid derivatives attached to a tricyclic skeleton were prepared and evaluated as 5α-reductase inhibitors. Structure activity relationships for these compounds in terms of rat epididymis (type 2) 5α-reductase inhibitory activit

Full text of DOI:10.1248/cpb.48.552

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