Synthesis of 5,6-difluoroarachidonic acid, a potential inhibitor of 5- lipoxygenase

DOI: 10.1016/0040-4039(96)00976-8

Source and publish data:

Tetrahedron Letters p. 4941 - 4944 (1996)

Update date:2022-08-02

Topics:

Authors:

Bildstein, Sylvia

Ducep, Jean-Bernard

Jacobi, Detlef

Zimmermann, Pascale

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Article abstract of DOI:10.1016/0040-4039(96)00976-8

The synthesis of 5,6-difluoroarachidonic acid 1 is described. The vicinal difluorinated double bond was prepared from the α-phenylthio-β- ketoester 4.

Full text of DOI:10.1016/0040-4039(96)00976-8

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