
Chemical and Pharmaceutical Bulletin p. 1168 - 1173 (1996)
Update date:2022-08-02
Topics:
Sai, Hiroshi
Ozaki, Yasuhiko
Hayashi, Kimiaki
Onoda, Yuichi
Yamada, Kenji
Trimebutine derivatives were synthesized by utilizing alkylation or acylation of isonitriles and nitrile as a key step. The colonic contractile effects of these compounds were examined, and T-1815 was found to have strong colonic propulsive activity.
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Doi:10.1080/10426509608029652
(1996)Doi:10.1038/nchem.2329
(2015)Doi:10.1016/0040-4020(96)00505-4
(1996)Doi:10.1021/ic960050y
(1996)Doi:10.1016/S0040-4039(99)01623-8
(1999)Doi:10.1039/j29690000638
(1969)