An efficient synthesis of substituted 3(4)-nitropyrroles from nitroalkenes and tosylmethyl isocyanides

Article abstract of DOI:10.1055/s-1996-4306

A series of 3(4)-nitropyrroles with alkenyl substituents in the 2- and 3-positions (or 3-position only) is synthesized efficiently in one operation by a base-induced addition of tosylmethyl isocyanide (TosMIC), or unsaturated homologs of TosMIC, to nitroa