Bioorganic and Medicinal Chemistry Letters p. 1991 - 1996 (1999)
Update date:2022-08-03
Topics:
Ciccarone, Terrence M.
MacTough, Suzanne C.
Williams, Theresa M.
Dinsmore, Christopher J.
O'Neill, Timothy J.
Shah, Daksha
Culberson, J. Christopher
Koblan, Kenneth S.
Kohl, Nancy E.
Gibbs, Jackson B.
Oliff, Allen I.
Graham, Samuel L.
Hartman, George D.
The design and syntheses of non-thiol inhibitors of farnesyl-protein transferase are described. Substitutions on an imidazolylmethyl-AMBA- methionine template gave a highly potent and cell-active inhibitor.
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Doi:10.1016/j.mcat.2018.05.016
(2018)Doi:10.1016/0957-4166(96)00253-4
(1996)Doi:10.1016/0040-4020(96)00579-0
(1996)Doi:10.1021/om960376e
(1996)Doi:10.1515/znb-1996-0723
(1996)Doi:10.1002/jhet.5570330321
(1996)
