Chemistry of Heterocyclic Compounds p. 408 - 417 (1996)
Update date:2022-08-04
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2-Acylindoles and 2-acylindole-3-carboxylic acids are readily alkylated at the nitrogen atom by haloalkanes in a superbasic medium (DMSO + NaOH). For the carboxylic acids, this reaction may proceed either entirely at the nitrogen atom, or at both the the
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