Tetrahedron Asymmetry p. 2017 - 2022 (1996)
Update date:2022-08-04
Topics:
Wuensche, Kerstin
Schwaneberg, Ulrich
Bornscheuer, Uwe T.
Meyer, Hartmut H.
Enantiomerically pure precursors of β-blockers (propranolol, alprenolol and 1-(isopropylamino)-3-p-methoxy-phenoxy-2-propanol) were synthesized. Key step is the lipase-catalyzed kinetic resolution of rac-3-hydroxy esters either by O-acylation using vinyl
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Doi:10.1016/0040-4020(96)00623-0
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(1996)
