Tetrahedron Letters p. 4711 - 4712 (1996)
Update date:2022-08-04
Topics:
Piettre, Serge R.
Girol, Catherine
Schelcher, Charles G.
A three-step sequence of reactions involving the lithium salt of diethyl difluoromethylphosphonate as a difluoromethyl carrier is shown to efficiently convert aliphatic and arylic aldehydes 2 into difluoromethyl ketones 1 via a unusual carbon-phosphorus bond scission.
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