Tetrahedron Letters p. 5045 - 5048 (1996)
Update date:2022-08-03
Topics:
Cutrona, Kellie J.
Sanderson, Philip E. J.
We describe an efficient synthesis of thrombin inhibitor L-370,618 (1) via β-lactam 2. The synthesis of 2 is carried out in six steps from 4- aminocyclohexane carboxylic acid, with a yield of 27%.
View MoreContact:+86-571-86491666
Address:SHI XIANG ROAD
Contact:86-575-86132822，86-575-86085355
Address:No.418 Dadao West Road,Qixing Street,Xinchang, Zhejiang Province, China.
Contact:+86-519-8525-2752
Address:Changzhou
Shandong Wanda Organosilicon New Material Co., Ltd
Contact:+86-21-54177116;54302881
Address:R1318 Greenland No. 3 Lane 58 Xinjian East Rd., Minhang
CGeneTech (Suzhou, China) Co., Ltd.
Contact:+86-512-62956962
Address:Room 101，Bld C11,218 Xinghu Rd.,Suzhou industrial Park
Doi:10.1039/c6nj02365g
(2016)Doi:10.1016/j.tetlet.2014.02.042
(2014)Doi:10.1107/S0108270193014234
(1994)Doi:10.1021/ic5003572
(2014)Doi:10.1021/acscombsci.5b00140
(2015)Doi:10.1002/jhet.5570230145
(1986)
