A stereoselective approach to the synthesis of aminoalcohols

DOI: 10.1016/0040-4039(96)01053-2

Source and publish data:

Tetrahedron Letters p. 5209 - 5212 (1996)

Update date:2022-07-30

Topics:

Authors:

Mordini, Alessandro

Valacchi, Michela

Pecchi, Sabina

Degl'Innocenti, Alessandro

Reginato, Gianna

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Article abstract of DOI:10.1016/0040-4039(96)01053-2

Amino alkoxy oxiranes have been isomerized to stereochemically pure amino alcohols, useful precursors for dipeptides isosteres, by treatment with the superbasic mixture butyllithium/diisopropylamine/potassium tert-butoxide.

Full text of DOI:10.1016/0040-4039(96)01053-2

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Product name:[(S)-1-((2R,3R)-3-Hydroxymethyl-oxiranyl)-2-phenyl-ethyl]-carbamic acid tert-butyl ester

Cas No:181357-02-8

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