Synthesis of the octahydroindole core of aeruginosins: A new bicyclic α-amino acid

DOI: 10.1016/0957-4166(96)00225-X

Source and publish data:

Tetrahedron Asymmetry p. 1899 - 1902 (1996)

Update date:2022-08-04

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Authors:

Bonjoch, Josep

Catena, Juanlo

Isabal, Esther

Lopez-Canet, Meritxell

Valls, Nativitat

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Article abstract of DOI:10.1016/0957-4166(96)00225-X

The first synthesis of 6-hydroxyoctahydroindole-2-carboxylic acid derivatives with a cis fusion in the azabicyclic nucleus is described. The synthesis involves a Birch reduction of O-methyl-L-tyrosine followed by an aminocyclization in acid medium to give

Full text of DOI:10.1016/0957-4166(96)00225-X

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