Chemistry Letters p. 621 - 622 (1996)
Update date:2022-09-26
Topics:
Yamaguchi, Jun-Ichi
Ueki, Masaaki
Treatment of L-N-protected 2-amino-5-bromopentanoic acid ester, which was prepared from protected L-glutamic acid, with sodium hydride in tetrahydrofuran (THF) proceeded to give the corresponding protected L-proline in high yield. On the other hand, the reaction of 2-aminobutyric acid derivative with sodium hydride gave the 1-aminocyclopropane-1-carboxylic acid derivative.
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