A convenient new route to 4-substituted benzo[de][3,6]phenanthrolin- 6(6H)-ones: Important intermediates in the synthesis of ring-A analogues of the cytotoxic marine alkaloid ascididemin

Article abstract of DOI:10.1080/00397919908086428

4-ethylthio- and (4-(4''-methylphenylthio)benzo[de][3,6]phenanthrolin- 6-(6H)-one have been synthesised in 4 steps from benzoquinone and then readily converted to the 4-amino (6d) and 4-methoxy (6c) analogues by nucleophilic substitution. Further elaborat

Full text of DOI:10.1080/00397919908086428

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Synthetic Communications: An
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A Convenient New Route
to 4-Substituted Benzo[de]
[3,6]Phenanthrolin-6(6H)-Ones:
Important Intermediates in the
Synthesis of Ring-A Analogues
of the Cytotoxic Marine Alkaloid
Ascididemin
Brent R. Copp a , Richard P. Hansen a , David R. Appleton a
, Brent S. Lindsay a , Chris J. Squire a , George R. Clark a &
Cliff E. F. Rickard a
a Department of Chemistry , University of Auckland , Private
Bag 92019, Auckland, New Zealand
Published online: 25 Sep 2007.
To cite this article: Brent R. Copp , Richard P. Hansen , David R. Appleton , Brent S. Lindsay ,
Chris J. Squire , George R. Clark & Cliff E. F. Rickard (1999) A Convenient New Route to
4-Substituted Benzo[de][3,6]Phenanthrolin-6(6H)-Ones: Important Intermediates in the
Synthesis of Ring-A Analogues of the Cytotoxic Marine Alkaloid Ascididemin, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic Organic
Chemistry, 29:15, 2665-2676, DOI: 10.1080/00397919908086428
To link to this article: http://dx.doi.org/10.1080/00397919908086428
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