
Tetrahedron Letters p. 6881 - 6884 (1996)
Update date:2022-07-29
Topics:
Nagasawa, Kazuo
Shimizu, Isao
Nakata, Tadashi
The C11-C23 segment of preswinholide A was stereoselectively synthesized based on the iterative construction of 1,3-polyol chains using a series of sequential reactions which involves the Sharpless asymmetric epoxidation of allyl alcohol and Pd-catalyzed hydrogenolysis of alkenyl oxirane with HCOOH as the key reactions.
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