Tetrahedron p. 13017 - 13026 (1996)
Update date:2022-07-29
Topics:
Dunn, Caroline
Gibson, Colin L.
Suckling, Colin J.
The synthesis of some 7,7-difluoro-7,8-dihydropterins and pterins with fluoroalkyl substituents at the 6 or 7 positions from fluorine-containing aliphatic precursors and suitably substituted pyrimidines is described. The fluorine-containing pterins were found to be very insoluble and also stable to nucleophiles and bases in dilute aqueous solution.
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Doi:10.1021/ja9611809
(1996)Doi:10.1021/jo982388a
(1999)Doi:10.1021/jo9613803
(1996)Doi:10.1039/dt9960004459
(1996)Doi:10.1021/ja962328r
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(1996)
