The unusual Baeyer-Villiger rearrangement of β-lactam aldehdyes: Totally stereoselective entry to cis-3-substituted 4-formyloxy-2-azetidinones

Article abstract of DOI:10.1016/0040-4039(95)00492-U

Baeyer-Villiger oxidation of 4-formyl-β-lactams 1 with m-chloroperbenzoic acid in dichloromethane at room temperature is shown to be a convenient method for the preparation of 4-formyloxy-β-lactams 2. Some reactions of novel compounds 2 are also described