
Tetrahedron Letters p. 8041 - 8044 (1996)
Update date:2022-08-04
Topics:
Kehler, Jan
Pueschl, Ask
Dahl, Otto
A phosphotriester method has been developed for solid phase synthesis of oligodeoxynucleoside phosphorodithioates. Couplings are performed by chemoselective oxygen activation of protected nucleoside dithiophosphate anions 1, 7, 8, 9 with 4-nitro-6-trifluo
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