Adenosine deaminase inhibitors. Synthesis and biological evaluation of chain modified analogs of (+)-EHNA

DOI: 10.1016/0960-894X(96)00439-8

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2417 - 2420 (1996)

Update date:2022-08-03

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Authors:

Pragnacharyulu, Palle V.P.

Lu, Pei-Jung

Abushanab, Elie

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Article abstract of DOI:10.1016/0960-894X(96)00439-8

Unsaturated chain modified analogs of (+)-EHNA have been prepared and evaluated as inhibitors of adenosine deaminase. The geometry appears to play a role in binding to the enzyme.

Full text of DOI:10.1016/0960-894X(96)00439-8

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