Journal of Organic Chemistry p. 568 - 577 (1997)
Update date:2022-08-02
Topics: Synthesis Cytotoxic Antimicrobial activity Pyrrole Alkaloid Intermediate Antitumor Activity Heterocyclic compound Formal total synthesis Quinoline Marine alkaloid Methyl group (-CH?) Methoxy group (-OCH?)
Roberts, David
Joule, John A.
Antonieta Bros
Alvarez, Mercedes
2-Amino-4-nitrophenol and 2-methoxy-5-nitroaniline were converted into the 5-nitroquinolines 6b and 6d, respectively, and then the latter into nitro-acetal 6f. 6,7-Dimethoxy-4-methylquinoline (6g) was nitrated at C-5 and then the methyl substituent conver
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