Synthesis and properties of 6-oxo-3,5-dicyano-1,4,5,6-tetrahydrospiro-(4′-R-cyclohexane-1′,4- pyridine)-2-thiols and -selenols

Article abstract of DOI:10.1007/BF01164713

By the interaction of a 4-R-cyclohexylidenecyanoacetic ester with cyanothio(seleno)acetarnide, 6-oxo-3,5-dicyano-1,4,5,6-tetrahydrospiro-(4′-R-cyclohexane-1′,4- pyridine)-2-thiols and -selenols have been obtained; these have also been synthesized from a cyclohexylidenecyanothioacetamide and cyanoacetic ester. These thiols and selenols have been used to prepare the corresponding disulfides, diselenides, and spiro systems, including the fragments alkylthio(seleno)tetrahydropyridine, thieno[2,3-b]pyridine, and 2,3-dihydrothiazolopyridine. 1997 Plenum Publishing Corporation.