Amino acids and peptides. XLVI. Introduction of carboxyl function into pyrazinone by using newly developed procedure for pyrazinone ring formation: Observation of immediate decarboxylation

DOI: 10.1248/cpb.44.2037

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Chemical and Pharmaceutical Bulletin p. 2037 - 2041 (1996)

Update date:2022-08-05

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Authors:

Taguchi, Hiroaki

Yokoi, Toshio

Okada, Yoshio

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Article abstract of DOI:10.1248/cpb.44.2037

The carboxyl function was easily introduced into a pyrazinone ring by means of a newly developed procedure for pyrazinone ring formation from Asp- or Glu-containing dipeptidyl chloromethyl ketones: during the reaction, rapid decarboxylation from a carboxy

Full text of DOI:10.1248/cpb.44.2037

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