Stereocontrolled synthesis of spirocyclopropane sugars and their application to asymmetric formation of tertiary chiral centres: A route to 2,2'-dialkylated pyranose subunit (C18-C23) of lasonolide A

Article abstract of DOI:10.1016/0040-4039(96)01991-0

A novel route to asymmetric formation of tertiary chiral centres of sugars via 2,2'-spirocyclopropane derivatives has been described. This route forms the basis of our proposed synthesis of the C₁₈-C₂₃ subunit of lasonolide A.