Boron-Catalyzed Aromatic C-H Bond Silylation with Hydrosilanes

Article abstract of DOI:10.1021/jacs.6b01349

Metal-free catalytic C-H silylation of a series of aromatic compounds such as N,N-disubstituted anilines with various hydrosilanes has been achieved for the first time using commercially available B(C₆F₅)₃ as a catalyst. This protocol features simple and neutral reaction conditions, high regioselectivity, wide substrate scope (up to 40 examples), Si-Cl bond compatibility, and no requirement for a hydrogen acceptor.