The synthesis of 4,5-methano congeners of α-kainic and α-allo-kainic acids as probes for glutamate receptors

DOI: 10.1016/S0040-4039(96)02105-3

Source and publish data:

Tetrahedron Letters p. 8971 - 8974 (1996)

Update date:2022-08-03

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Authors:

Hanessian, Stephen

Ninkovic, Sacha

Reinhold, Ulrich

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Article abstract of DOI:10.1016/S0040-4039(96)02105-3

The synthesis of diastereomeric 4,5-methano-L-proline 3-acetic acids is described starting from D-serine. The key reactions include a free-radical carbocyclization and an acid-catalyzed destannylative cyclopropanation of an iminium ion intermediate. Copyright (C) 1996 Elsevier Science Ltd.

Full text of DOI:10.1016/S0040-4039(96)02105-3

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