A convenient, large-scale synthesis of abiraterone acetate [3β-acetoxy-17-(3-pyridyl)androsta-5,16-diene], a potential new drug for the treatment of prostate cancer

Full text of DOI:10.1080/00304949709355175

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Organic Preparations and Procedures
International: The New Journal for
Organic Synthesis
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A CONVENIENT, LARGE-SCALE
SYNTHESIS OF ABIRATERONE
ACETATE [3β-ACETOXY-17-(3-
PYRIDYL)ANDROSTA-5,16-DIENE],
A POTENTIAL NEW DRUG FOR THE
TREATMENT OF PROSTATE CANCER
Gerard A. Potter a b , Ian R. Hardcastle a & Michael Jarman a
a Cancer Research Campaign Laboratory, CRC Centre for Cancer,
Therapeutics at the Institute of Cancer Research, 15 Cotswold Road,
Sutton, Surrey, SM2 5NG, UK
b Chiroscience Ltd, Cambridge Science Park, Milton Road,
Cambridge, CB4 4WE, UK
Version of record first published: 09 Feb 2009.
To cite this article: Gerard A. Potter , Ian R. Hardcastle & Michael Jarman (1997): A CONVENIENT,
LARGE-SCALE SYNTHESIS OF ABIRATERONE ACETATE [3β-ACETOXY-17-(3-PYRIDYL)ANDROSTA-5,16-
DIENE], A POTENTIAL NEW DRUG FOR THE TREATMENT OF PROSTATE CANCER, Organic Preparations
and Procedures International: The New Journal for Organic Synthesis, 29:1, 123-128
To link to this article: http://dx.doi.org/10.1080/00304949709355175
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