Journal of labelled compounds and radiopharmaceuticals p. 1 - 10 (1997)
Update date:2022-07-30
Topics:
Tadikonda, Praveen K.
Lacy, James M.
Rigdon, Michael G.
Deluca, Hector F.
The synthesis of 9-cis-retinoic acid starting from 2,2,6-trimethylcyclohexanone is described. The same methodology was extended for the synthesis of deuterium and tritium labeled 9-cis-retinoic acid with high specific activity (73 Ci/mmol). In this methodology, a Grignard reaction was utilized for introducing three tritium atoms simultaneously in the final synthetic steps.
View MoreContact:86-310-8067016
Address:East Fuhua Road,Tiexi Chemical Industrial Estate,Hebei,China
Hangzhou Showland Technology Co., Ltd.
Contact:86-571-88920516
Address:ROOM2118,NO.553,WENSAN ROAD,HANGZHOU,CHINA
Contact:+86-27-85733560
Address:NO.308,QINGNIAN RD.,WUHAN,CHINA
Nanjing Norris Pharm Technology Co., Ltd.
Contact:+86-13901585132
Address:2 Qiande Road, Jiangning sciencepark Hi-Tech Zone, Nanjing, P.R.China
Shandong united-rising pharmaceutical cooperation.,ltd.
Contact:008653187965009
Address:171No., Jing5 Road, Shizhong District, Jinan, China
Doi:10.1002/chem.19970030112
(1997)Doi:10.1021/ol402559z
(2013)Doi:10.1016/0008-6215(93)84071-D
(1993)Doi:10.1021/jo01103a036
(1958)Doi:10.1016/S0960-894X(97)00070-X
(1997)Doi:10.1021/jacs.1c00243
(2021)