Synthesis of the C1-C9 segment of epothilons

DOI: 10.1016/S0040-4039(96)02493-8

Source and publish data:

Tetrahedron Letters p. 1359 - 1362 (1997)

Update date:2022-08-03

Topics:

Authors:

Claus, Eckhard

Pahl, Axel

Jones, Peter G.

Meyer, Hartmut M.

Kalesse, Markus

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(96)02493-8

The C1-C9 segment of epothilons was generated by an aldol reaction between chiral aldehyde 3 and ethyl ketone 4. Removal of the TBS protecting groups and debenzylation generated spiro ketal 13 which was analyzed by X-ray crystallography.

Full text of DOI:10.1016/S0040-4039(96)02493-8

Products guided by the article

Product name:[(S)-3,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2,2-dimethyl-pentyloxymethyl]-benzene

Cas No:187527-29-3

R&D Labs maybe for 187527-29-3

Jiangxi Lanqi Fine Chemical S&T Co., Ltd.

Contact:+86-21-64891143

Address:XinJiShan Industrial Area, Zhangshu City, JiangXi Province, China
Beijing Mashi Fine Chemical Co.,Ltd.

Contact:+86-10-61271592

Address:Room 506, Section B, Kaichi Mansion, Industrial Development
Joyochem Co., Ltd.

website:https://sdjingyuan.lookchem.com/

Contact:86-531-82687998

Address:Factory Building 11, Jinan Comprehensive free trade zone, Shandong, China
Beijing ZhongDaXinHe Chemical Product Co.,Ltd(expird)

Contact:010-52876516

Address:tongzhoubeiyuan
Anhui Biochem United Pharmaceutical Co., Ltd.

Contact:0086 551 5167062 / 5228268

Address:No. 30 Hongfeng Road, Hi-Tech Development Zone, Hefei (230088), China

Relevant to this article

Asymmetric synthesis of dideazafolate antitumor agents via amidomethylation of nonracemic oxazolidinone imidates, synthesis of LY309887, a cytotoxic dideazafolate analog related to lometrexol

Doi:10.1016/S0040-4039(96)02418-5
(1997)
Synthesis of 1,2,4-trioxanes and 1,2,4-trioxepanes by N-halogenosuccinimide-mediated cyclisations of unsaturated hydroperoxyacetals

Doi:10.1039/a605616d
(1997)
Synthesis and chemiluminescent property of the novel 1,2-Dioxetanes containing an acridane-10-acetate moiety as the luminophore and trigger unit

Doi:10.1016/S0040-4039(96)02463-X
(1997)
Synthesis and incorporation of carbocyclic nucleosides into a hammerhead ribozyme domain-RNase resistance and catalytic activity

Doi:10.1039/CC9960001623
(1996)
Novel tele nucleophilic aromatic substitutions in α-(benzotriazol-1-yl)alkyl aryl ketones

Doi:10.1016/S0040-4039(96)02455-0
(1997)
Multiple hindered rotators in a gyroscope-inspired tribenzylamine hemicryptophane

Doi:10.1021/jo102480s
(2011)

Article Doi