Tetrahedron Letters p. 1359 - 1362 (1997)
Update date:2022-08-03
Topics:
Claus, Eckhard
Pahl, Axel
Jones, Peter G.
Meyer, Hartmut M.
Kalesse, Markus
The C1-C9 segment of epothilons was generated by an aldol reaction between chiral aldehyde 3 and ethyl ketone 4. Removal of the TBS protecting groups and debenzylation generated spiro ketal 13 which was analyzed by X-ray crystallography.
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(2011)
