Haloacetylated Enol Ethers. 7 [7]. Synthesis of 3-Aryl-5-trihalomethylisoxazoles and 3-Aryl-5-hydroxy-5-trihalomethyl-4,5-dihydroisoxazoles

Article abstract of DOI:10.1002/jhet.5570330612

β-Aryl-β-methoxyvinyl trihalomethyl ketones 1a-g, 2a-g [aryl = p-YC₆H₄ where Y= H, Me, OMe, F, Cl, Br, NO₂] are cyclocondensed with hydroxylamine hydrochloride to afford the 3-aryl-5-hydroxy-5-trihalomethyl-4,5-dihydroisox