Asymmetric Synthesis of Sulfinimines: Applications to the Synthesis of Nonracemic β-Amino Acids and α-Hydroxy-β-amino Acids

Article abstract of DOI:10.1021/jo00050a007

Asymmetric oxidation of sulfenimines 1 affords sulfinimines 2 (88-90percent ee) which are chiral ammonia imine synthons useful in the enantioselective synthesis of β-amino acids and α-hydroxy-β-amino acids such as the C-13 side chain of taxol (2R,3S)-7.