Synthesis and antitumor activity of fused quinoline derivatives. IV. Novel 11-aminoindolo[3,2-b]quinolines

DOI: 10.1248/cpb.45.406

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 406 - 411 (1997)

Update date:2022-08-05

Topics:

Authors:

Takeuchi, Yasuo

Oda, Toshiaki

Chang, Ming-Rong

Okamoto, Yoko

Ono, Junko

Oda, Yoko

Harada, Kyoko

Hashigaki, Kuniko

Yamato, Masatoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.45.406

Indolo[3,2-b]quinoline derivatives (1) having various amine moieties were prepared and their antitumor activities against P388 leukemia in mice were evaluated, for the purpose of gaining an insight into the role of the amine moiety in the antitumor activity and searching for an effective amine moiety. Introduction of a methylene group between the phenyl group and amino or methanesulfonamido group resulted in decrease or loss of activity.

Full text of DOI:10.1248/cpb.45.406

NII-Electronic Library Service

Products guided by the article

Product name:N-(3-methoxy-4-nitro)benzylmethanesulfonamide

Cas No:188630-71-9

R&D Labs maybe for 188630-71-9

WuHan rongfashun BioChemical co., LTD

Contact:02788866139

Address:No.95 LuoYu Road,Wuhan
Maithili Life Sciences

Contact:+91 9963263336

Address:Plot#146A, IDA Mallapur, Hyderabad - 500072
Jiangxi Hito Chemical Co., Ltd.

Contact:+86-792-3170318

Address:No. 6, Tianhong Ave., Xinghuo Industry Park, Yongxiu, Jiujiang, Jiangxi, China
Zhejiang Linhai Xinhua Chemicals Factory

Contact:0086-13661858911

Address:Xunqiao Development Zone, Linhai, Zhejiang, China
Jiangsu Chiatai Qingjiang Pharmaceutical Co.,Ltd

Contact:+86-517-86283327

Address:9 North Hantai Road, Huaian, China

Relevant to this article

Application of the Grubbs ring-closing metathesis for the construction of a macrocyclic ansa-bridge. Synthesis of the tricyclic core of roseophilin

Doi:10.1016/S0040-4039(97)00424-3
(1997)
Bis C-glycosylated diphenylmethanes for stable glycoepitope mimetics

Doi:10.1055/s-1999-2738
(1999)
Electrochemical study of structural effects in complexation of nano-baskets: Calix[4]-1,2-crown-3,-crown-4,-crown-5,-crown-6

Doi:10.1080/15533174.2012.680131
(2012)
Factors influencing the regioselectivity of the oxidation of asymmetric secondary amines with singlet oxygen

Doi:10.1002/chem.201500121
(2015)
Asymmetric synthesis of α-monofluoromethyl- and α- difluoromethylbenzylamines through regioselective hydrogenolysis

Doi:10.1016/j.jfluchem.2005.01.009
(2005)
Doi:10.1007/BF02636127
(1995)

Article Doi