Synthesis and antitumor activity of fused quinoline derivatives. IV. Novel 11-aminoindolo[3,2-b]quinolines

DOI: 10.1248/cpb.45.406

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 406 - 411 (1997)

Update date:2022-08-05

Topics:

Authors:

Takeuchi, Yasuo

Oda, Toshiaki

Chang, Ming-Rong

Okamoto, Yoko

Ono, Junko

Oda, Yoko

Harada, Kyoko

Hashigaki, Kuniko

Yamato, Masatoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.45.406

Indolo[3,2-b]quinoline derivatives (1) having various amine moieties were prepared and their antitumor activities against P388 leukemia in mice were evaluated, for the purpose of gaining an insight into the role of the amine moiety in the antitumor activity and searching for an effective amine moiety. Introduction of a methylene group between the phenyl group and amino or methanesulfonamido group resulted in decrease or loss of activity.

Full text of DOI:10.1248/cpb.45.406

NII-Electronic Library Service

Products guided by the article

Product name:N-(3-methoxy-4-nitro)benzylmethanesulfonamide

Cas No:188630-71-9

R&D Labs maybe for 188630-71-9

GIHI CHEMICALS CO.,LIMITED

Contact:+86-571-86217390

Address:No.567 Dengcai Street,Sandun,Westlake District,Hangzhou310030,Zhejiang,China.
ClickChem Technology Co., Limited

Contact:+86-0310-6519966/0531-52893837

Address:No.750 Shunhua Road, High-Tech Zone, Jinan city, Shandong China
ShangHai Original Economy-Trade Develop Co.,Ltd.,

Contact:86-21-68552131

Address:shanghai
Huangshan Violet Biological Technology Co., Ltd

Contact:+86-559-2335676

Address:16-201 JinShanYuan,JiangNan New City,TunXi District,HuangShan City,AnHui Province,China
Shuanghe Bio-Technology Limited(expird)

Contact:+86-571-61710758,18968016640

Address:Jinqiao north road 916# Fuyang

Relevant to this article

Application of the Grubbs ring-closing metathesis for the construction of a macrocyclic ansa-bridge. Synthesis of the tricyclic core of roseophilin

Doi:10.1016/S0040-4039(97)00424-3
(1997)
Bis C-glycosylated diphenylmethanes for stable glycoepitope mimetics

Doi:10.1055/s-1999-2738
(1999)
Electrochemical study of structural effects in complexation of nano-baskets: Calix[4]-1,2-crown-3,-crown-4,-crown-5,-crown-6

Doi:10.1080/15533174.2012.680131
(2012)
Factors influencing the regioselectivity of the oxidation of asymmetric secondary amines with singlet oxygen

Doi:10.1002/chem.201500121
(2015)
Asymmetric synthesis of α-monofluoromethyl- and α- difluoromethylbenzylamines through regioselective hydrogenolysis

Doi:10.1016/j.jfluchem.2005.01.009
(2005)
Doi:10.1007/BF02636127
(1995)

Article Doi