Synthesis, molecular modeling, and biology of the 1-benzyl derivative of APDC - an apparent mGluR6 selective ligand

DOI: 10.1016/S0960-894X(97)00068-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 601 - 606 (1997)

Update date:2022-07-30

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Authors:

Tueckmantel, Werner

Kozikowski, Alan P.

Wang, Shaomeng

Pshenichkin, Sergey

Wroblewski, Jarda T.

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Article abstract of DOI:10.1016/S0960-894X(97)00068-1

The synthesis of the 1-benzyl derivative of (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid (1-benzyl-APDC) starting from cis-4-hydroxy-D-proline is disclosed together with a study of the activity of this compound at metabotropic glutamate receptors (mGl

Full text of DOI:10.1016/S0960-894X(97)00068-1

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