Synthesis, molecular modeling, and biology of the 1-benzyl derivative of APDC - an apparent mGluR6 selective ligand

DOI: 10.1016/S0960-894X(97)00068-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 601 - 606 (1997)

Update date:2022-07-30

Topics:

Authors:

Tueckmantel, Werner

Kozikowski, Alan P.

Wang, Shaomeng

Pshenichkin, Sergey

Wroblewski, Jarda T.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00068-1

The synthesis of the 1-benzyl derivative of (2R,4R)-4-aminopyrrolidine-2,4-dicarboxylic acid (1-benzyl-APDC) starting from cis-4-hydroxy-D-proline is disclosed together with a study of the activity of this compound at metabotropic glutamate receptors (mGl

Full text of DOI:10.1016/S0960-894X(97)00068-1

Products guided by the article

Product name:(2R,4R)-4-Amino-pyrrolidine-2,4-dicarboxylic acid dibenzyl ester

Cas No:188966-64-5

R&D Labs maybe for 188966-64-5

Wuxi Olite Chemical Co., Ltd.

Contact:86-510-82853889

Address:Rm.3732, No.18-2,Yonghe Rd.,Wuxi,Jiangsu,214023,China
Hefei EnliPharma Tecnology Co.,Ltd

Contact:0086-551-66399836

Address:Qing Cheng ShuiXiang Building 805, Mengcheng North Road , ShuangFeng Economic Development Zone Anhui HeFei
NOVASYNCS CO., LTD

Contact:0512-63006287

Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA
Hubei Lingsheng Pharmaceuticals Co., Ltd.

Contact:+86-0710-3538058

Address:Xiangyang City Xiangcheng Economic Development Zone, Hubei Province
Shandong Xinke Petrochemical Co., Ltd.

Contact:+86-546-7277016

Address:Gudao Industrial Park, Hekou District, Dongying, Shandong Province, China

Relevant to this article

Design and development of 1,3,5-triazine-thiadiazole hybrids as potent adenosine A2A receptor (A2AR) antagonist for benefit in Parkinson's disease

Doi:10.1016/j.neulet.2020.135222
(2020)
An unusual side reaction in the rearrangement of 3,4,6-tri-O-acetyl-1,2-O-(allyloxyethylidene)-β-D-mannopyranose with tms-triflate: Formation of an α(1→2)-linked disaccharide

Doi:10.1080/07328309708006524
(1997)
Simplified and versatile access to low valent Ni complexes by metal-free reduction of Ni^II precursors

Doi:10.1039/c9dt00668k
(2019)
STEREOSPECIFIC SYNTHESIS OF CARBOCYCLIC NUCLEOSIDES FROM 2-AZABICYCLO-<2.2.1>HEPTAN-3-ONES VIA SODIUM BOROHYDRIDE MEDIATED CARBON-NITROGEN BOND CLEAVAGE

Doi:10.1016/S0040-4039(00)99542-X
(1989)
Interaction of triplet C₆₀ with p-tert-butyl-calixarenes and their complexes with pyridine derivatives

Doi:10.1039/b301633a
(2003)
Synthesis and α-adrenergic activity of 2- and 6-methyl-substituted (3,4-dihydroxyphenyl)-3-piperidinols

Doi:10.1016/S0223-5234(97)83974-8
(1997)

Article Doi