Synthesis of enantiomerically pure desmethyl C,D-Ring derivative of paclitaxel (Taxo(TM)) via asymmetric Diels-Alder reaction of 2-siloxyfuran

DOI: 10.1016/S0040-4039(97)00454-1

Source and publish data:

Tetrahedron Letters p. 2725 - 2728 (1997)

Update date:2022-08-04

Topics:

Authors:

Sha, Chin-Kang

Lee, Shin-Jen

Tseng, Wei-Hong

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)00454-1

Cycloadduct 3 of the asymmetric Diels-Alder reaction of 2-siloxyfuran 2 and dimethyl acetylenedicarboxylate was converted into the enantiomerically pure desmethyl C,D-ring derivative 13 of Paclitaxel.

Full text of DOI:10.1016/S0040-4039(97)00454-1

Products guided by the article

Product name:(1S,4S)-1-[(S)-2,2-Bis-(4-methoxy-phenyl)-[1,3]dioxolan-4-yl]-4-(tert-butyl-dimethyl-silanyloxy)-7-oxa-bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic acid dimethyl ester

Cas No:189130-15-2

R&D Labs maybe for 189130-15-2

Jiangsu Hualun Chemical Industry Co., Ltd

website:http://www.hualunchem.com

Contact:+86-0514-86464168 86507985

Address:39# Middle Renmin Road, Dinghuo Town
Shreeji pharma international

Contact:0091-265-2313036

Address:311, ATLANTIS HEIGHTS SARABHAI MAIN ROAD,VADIWADI ,VADODARA
Tianjin Boron PharmaTech Co.,Ltd.(expird)

Contact:86-022-59845187

Address:B9-401, Tianda Science Park,No.80,4th Avenue,TEDA,Tianjin, China
SunaTech Inc.

Contact:+86 512 6287 2180

Address:398 Ruoshui Road, Suzhou Industrial Park, Suzhou, Jiangsu, P. R. China
Shanghai Longschem Co.,Ltd

Contact:021-36356756

Address:Room601,Building No.14,280 Yangcheng Road,Shanghai

Relevant to this article

Ten isomeric five-ring bent-core mesogens: The influence of the direction of the carboxyl connecting groups on the mesophase behaviour

Doi:10.1039/b508488a
(2005)
Synthesis of 4-(Acylacetyl)-1-phenyl-2-pyrazolin-5-ones from 3-Acyl-2H-pyran-2,4(3H)-diones. Their Synthetic Applications to Functionalized 4-Oxopyrano<2,3-c>pyrazole Derivatives.

Doi:10.1021/jo00170a041
(1983)
Surface-mediated solid phase reactions: A simple and new method for the synthesis of α-aminophosphonates under solvent-free conditions

Doi:10.1246/cl.2001.880
(2001)
Design of the First-in-Class, Highly Potent Irreversible Inhibitor Targeting the Menin-MLL Protein–Protein Interaction

Doi:10.1002/anie.201711828
(2018)
Copper-Catalyzed Hydroarylation of Internal Alkynes: Highly Regio- and Diastereoselective Synthesis of 1,1-Diaryl, Trisubstituted Olefins

Doi:10.1021/acscatal.7b01847
(2017)
Doi:10.1039/CT9140501152
(1914)

Article Doi