Synthesis and antiviral evaluation of N-b-D-ribosides of ergot alkaloids

Article abstract of DOI:10.1080/07328319708002525

N-β-D-Ribosides of agroclavine (1), elymoclavine (2), lysergene (4), lysergol (3), and 9,10-dihydrolysergol (5) were prepared by SnCl₄ catalyzed ribosylation of their TMS derivatives with 1-O-acetyl-2,3,5-tri-O-benzoyl- β-D-ribofuranose. None of the new compounds exhibited activity against HIV or other viruses tested.

Full text of DOI:10.1080/07328319708002525

Nucleosides and Nucleotides
ISSN: 0732-8311 (Print) (Online) Journal homepage: http://www.tandfonline.com/loi/lncn19
Synthesis and Antiviral Evaluation of N-β-D-
Ribosides of Ergot Alkaloids
Vladimír Křen , Alois Pískala , Petr Sedmera , Vladimír Havlíěek , Věra
Přikrylová , Myriam Witvrouw & Erik De Clercq
To cite this article: Vladimír Křen , Alois Pískala , Petr Sedmera , Vladimír Havlíěek , Věra
Přikrylová , Myriam Witvrouw & Erik De Clercq (1997) Synthesis and Antiviral Evaluation
of N-β-D-Ribosides of Ergot Alkaloids, Nucleosides and Nucleotides, 16:1-2, 97-106, DOI:
10.1080/07328319708002525
To link to this article: http://dx.doi.org/10.1080/07328319708002525
Published online: 20 Aug 2006.
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Date: 29 May 2016, At: 23:32