Thiazolidinediones with thyroid hormone receptor agonistic activity

DOI: 10.1248/cpb.47.1348

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1348 - 1350 (1999)

Update date:2022-08-04

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Authors:

Ebisawa, Masayuki

Inoue, Noriko

Fukasawa, Hiroshi

Sotome, Tomomi

Kagechika, Hiroyuki

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Article abstract of DOI:10.1248/cpb.47.1348

Several thiazolidinedione derivatives (3-7) were designed and synthesized as candidate thyromimetic drugs. Among them, the dihydrogenated compounds, such as 5-2-[[4-(3-tert-butyl-4-hydroxyphenyl)oxy-3,5- diiodophenyl]ethyl]-2,4-thiazolidine-dione (6b) and

Full text of DOI:10.1248/cpb.47.1348

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