Enantiomers synthesis of the four catechin diastereomer derivatives

Article abstract of DOI:10.1016/S0040-4039(97)00552-2

Asymmetric dihidroxylalion of (E)-1 -(3,4-dimethoxyphenyl)-3-2-methoxy-methyl-4,6- dimethoxy-phenyl)-propene with AD-mix-α or AD-mix-β in the presence of methanesulfonamide, followed by acid catalysed cyclization, afforded the four catechin diastereomers in high enantiomeric excesses and yields.