Tetrahedron p. 4787 - 4790 (1997)
Update date:2022-08-04
Topics:
Albanese, Domenico
Landini, Dario
Penso, Michele
A study on the ring opening of a number of epoxides 1 with trifluoroacetamide (2) under solid-liquid phase transfer catalysis (SL-PTC) conditions has been performed. The reaction is completely regioselective affording β-amido alcohols 3 deriving from the attack of the nucleophile to the less substituted carbon atom of the oxirane ring.
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