Tetrahedron Letters p. 2197 - 2200 (1997)
Update date:2022-09-26
Topics:
Mattern, Ralph-Heiko
Gunasekera, Sarath P.
McConnell, Oliver J.
The synthesis of microcolin analogs is described using an approach that could be of considerable practical interest for structure-activity studies on microcolin and related peptides. This synthetic pathway is more efficient than the methods reported to date, and allows the variation of the Xaa-pyrrolin-2-one unit of these molecules, which has been shown to be crucial for the biological activity.
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(1997)
