Stereospecific synthesis of (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid, a selective agonist of metabotropic glutamate receptors

DOI: 10.1016/S0957-4166(97)00060-8

Source and publish data:

Tetrahedron Asymmetry p. 825 - 827 (1997)

Update date:2022-07-30

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Authors:

Ma, Dawei

Ma, Jingyuan

Dai, Lixin

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Article abstract of DOI:10.1016/S0957-4166(97)00060-8

(1S,3R)-Aminocyclopentane-1,3-dicarboxylic acid 1, a widely used metabotropic glutamate receptor agonist has been synthesized. Hydrolysis followed by Curtius rearrangement of 5 derived from dimethyl (S)-malate gave 6 with excellent diastereofacial selecti

Full text of DOI:10.1016/S0957-4166(97)00060-8

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Product name:Butanedioic acid, (diphenylmethoxy)-, dimethyl ester, (S)-

Cas No:190510-40-8

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